Autophagy Fasting: The Mystery Explained

Autophagy Fasting: The Mystery Explained

INTERMITTENT FASTING
Simply put, intermittent fasting isn't a diet. Intermittent fasting is a meal timing plan. So basically what you're doing is you're focusing on a specific period of time in which you are abstaining from food and abstaining from calories and then you have a set period of time in which you consolidate all of your food, all of your calories. You're basically going for an extended period of time and not eating , but fasting. And then you're going into a period of time where you are eating, your fed window. So one of the biggest problems that people make with fasting is they overthink it.


AUTOPHAGY 'to eat thyself.' Recycle the cellular parts that are damaged or not being used. In this video I talk about Autophagy and how to achieve Autophagy through Intermittent Fasting. Intermittent Fasting is a great way to get into a Keto Diet and ultimately what you need to do to achieve Autophagy.


KETONES AND AUTOPHAGY.

Baby Boomers endured the most abuse from the medical establishment over the last 40 years. Before it’s too late, we in the medical establishment might have a few years to redeem some of the atrocious recommendations that your generation lived were given. The science of how your body eats itself is something you should pay attention to and master.


Autophagy removes debris found inside your body’s cells. All those years of poorly fed brain cells, sleep deprived hearts, smoking in your early years, and becoming fatter than any generation before has left you with lots of crusty cells. The debris within your tissue has been there for years. If you are overweight, this debris has been around for as long as those extra pounds have insulated you. PLUS ten years.

 
 

Intermittent Fasting with Keto Diet explained



*This content is strictly the opinion of Annette Bosworth, MD. The content informs and educates viewers. Medical advice is not given on this website. Your personal physician gives the medical advice and treatment specific to your situation. Dr Boz channel only educates. Consult your doctor or qualified health professional regarding specific health questions. Neither Dr. Bosworth nor the publisher of this content takes responsibility for possible health consequences of any person(s) receiving this educational content. Ask your health advisors before beginning any nutritional supplement or lifestyle program.



read more ::



00:00

Hi, I'm Dr. Bosworth and welcome back I have another video for you today and a blog post along with it

00:06

That's about something very strange called

00:09

Autophagy. If you've never heard of that word that makes you normal

00:13

But the Nobel Prize in medicine in 2016 went to exactly this topic and it couldn't be more

00:21

Appropriate for the timing of this information.

00:29

I contend that every baby boomer needs to know this information

00:32

So tune in and put on your science caps

00:35

Cuz this might be a little sciency II but I'll walk you through it autophagy. It literally means to eat

00:43

thyself autophagy eat thyself

00:46

sounds super weird, right? The Nobel Prize in medicine in 2016 went to

00:52

Yoshinori Ohsumi who's the man who's been looking into this strange word called autophagy for his

00:59

practically his whole lifetime. We've always known that the body has a way of cleaning up debris inside ourselves inside our bodies and

01:08

keeping that level of

01:10

junk, if you would, low and that it worked better in some people and not so much in others

01:16

but we didn't know how it turned on or how it worked and how to turn it off. This Nobel Prize in

01:22

2016 outlined how this works. Baby boomers pay attention this

01:27

understanding of autophagy might be

01:30

medicine's saving grace for that

01:33

generation of bad advice that we've given you.

01:36

Your generation has endured more procedures, more surgeries, had more chronic diseases that

01:44

escalate in your lifetime and

01:46

has made you fatter than any generation ever documented before.

01:52

This might be the one thing in your lifetime that could reign in or hone in that we've given to your whole generation

02:00

So this message is specifically targeted at baby boomers and why they should care.

02:05

Brain biopsies tell the story the best. We know that when brain cells and brain function is doing well

02:11

we can look at tissue from that brain under a microscope and find very little debris

02:16

very little junk also called plaques or neurofibrillary tangles that

02:23

this level of. . . think of it as a rusty leftover cell parts that are hanging out in your brain and

02:30

the dump truck should come along pick it up and scoop it away,

02:33

but for some reason in your brain, it hasn't done a good job of that.

02:37

A little bit of junk hanging out?

02:39

no problem, but as it builds up over the years it becomes a predictor for diseases like Alzheimer's, Parkinson's,

02:47

and memory loss just in general.

02:50

but before you ever have a day where you miss a

02:54

memory; where you glitch and can't think of a word; if

02:57

we would back up in your brain about five years

03:00

we could see that there were debris or these plaques building up to begin with

03:05

By the time you come to an office visit and say doc there's something wrong with my memory

03:10

we're usually 15 years into a whole pile of

03:14

junky debris throughout your brain and

03:17

autopsies have proven that. When we look at the function of a brain and

03:21

we study how badly it's impacted

03:24

one of the predictors for function is how many of these plaques or neurofibrillary tangles are hanging out in their brains.

03:30

You want those to go away?

03:32

That's autophagy! Autophagy is the cellular process that says hey

03:37

this cell isn't working very well. Let's clean it up and see if we can make it function better.

03:44

I want to compare that to another "sciency" word called apoptosis

03:49

which is the programmed cell death.

03:51

Every one of the cells in our body has a lifespan

03:55

it's supposed to live for so long, but you can sell yourself short and have those cells not live as long or

04:02

Have them live even longer than expected

04:05

based on this process that ignites

04:09

programmed cell death.

04:10

If the cell is swollen and inflamed and living under chronic stress

04:16

We know that the cell life is shorter that those cells don't live as long and I'm talking about heart cells, brain cells, lung cells

04:24

Every cell in the body turns over at a certain interval.

04:27

But under times of chronic high stress and specifically chronic inflammation those cells don't live as long.

04:34

Apoptosis says hey this cell life is used up. It's over and

04:40

throw the cell away.

04:41

Compare that to

04:43

autophagy, which says hey, this cell has a lot of junk in it. We're gonna clean up the different parts of that cell and

04:50

recycle that nourishment for the rest of the body. Why should you care?

04:54

All this sounds way over most people's heads and they don't care but you should care if you're a baby boomer and you're overweight.

05:01

The answer for why people should care would be the flabby skin left over after weight loss.

05:09

It's embarrassing, the number of baby boomers that have said these words to me, "Yeah, doc

05:13

I know I should lose weight, but you know, it would leave me with too many wrinkles." Yes, they say that!

05:20

I have good news for you!

05:22

If you induce autophagy

05:25

during your weight loss your body will recycle those deformed cells

05:29

that made those wrinkles in the first place. Yes, autophagy is a process where it recycles and uses the

05:37

unused or deformed cells in your body and

05:40

recycles them for nourishment. One more example--

05:43

Let's take the tale of two people losing a hundred pounds. A hundred pounds is a lot of weight and

05:50

when you do that, you'll find that most people in today's low calorie, otherwise known as torture diets,

05:59

trickle food in at this low level

06:02

nutrition as their body metabolism shuts down a little bit further every day, every day, every month and

06:09

indeed they lost a hundred pounds.

06:11

but the difference between someone who's lost a hundred pounds with a low-calorie diet as to someone who's lost a

06:19

hundred pounds while igniting their autophagy

06:23

is a skin curtain

06:25

Skin curtains are the word that we in medicine used for the leftover flabby skin

06:30

In the arms or in the abdomen when people have lost massive amounts of weight

06:35

The solution that medicine has come up with when that happens is of course a surgery.

06:41

The surgeon goes in and he will trim off the extra skin

06:45

But under the skin there is way more to the story the blood vessels the connective tissue the place where all those fat cells

06:51

Were filled with stored fat

06:54

Still exist in these patients, they weren't recycled. They weren't gobbled up like they would be in autophagy.

07:02

Autophagy ignites the process where the body absorbs not just the skin cells

07:07

But the blood vessels and the connective tissue and all of that other stuff

07:13

Found inside the human body when fat has been filling a space and now the fat is gone

07:20

but that stuff is all left over. In autophagy

07:24

the system uses those cells as a form of nourishment and

07:29

You can see the weight loss keeps the skin held tightly to their muscles. Autophagy is a big topic of conversation

07:37

Around those people losing a lot of weight

07:39

but it should be just as important for people who are trying to undo a

07:43

Chronically inflamed brain or heart or other system in your body

07:48

that chronic inflammation has left the junk and the debris hanging out. The body simply didn't have the resources or the

07:56

Chemistry set present inside the body to go gobble up that extra debris inside the cells. So autophagy's a good thing.

08:04

Inducing it means that you need a certain chemistry set. And what does that?

08:09

in a word- Fasting.

08:11

Yes. I know this word sounds like a curse word when I first introduced it to patients, but

08:17

Fasting sets up a chemistry set that allows the body to find resources throughout the system

08:24

it's really important that you distinguish the difference between a low calorie diet, which is a trickle of

08:32

calories coming in,

08:35

in comparison to fasting which is zero calories coming in. If I take a patient who's on a standard American diet with

08:42

100 to 300 carbohydrates a day and I want them to induce autophagy

08:47

I will need to keep no calories around for about

08:52

72 hours before their system

08:55

induces autophagy. If you've ever tried to do that from a high carbohydrate state,

09:00

you won't like the person who's forcing you to do it.

09:03

It's not comfortable. People have lots of hunger pains. The transition from a high carb situation to zero calories is

09:12

painful, it causes hunger.

09:13

It's very unsettling. Now compare that to someone who's in ketosis

09:18

who's using fat as their fuel most of the time. They have less than 20 carbohydrates that come in a day and

09:25

when we stop their calories, you can see autophagy ignite within as little as 12 hours.

09:32

More often a

09:34

autophagy status is guaranteed by 24 hours or 36 hours, but you can see the process begin in as little as 12 hours.

09:42

That can happen every day in one of my ketosis patients

09:46

Suppertime being around five o'clock or six o'clock if they fast until morning

09:50

Which is eight hours when they're sleeping with

09:53

no calories in between you can see their bodies ignite a little bit of autophagy every day

09:59

This is amazing for what it does to the cleanup crew inside their 70, 80, 90 year-old bodies.

10:05

I have a couple of patients who come to my keto support group every week.

10:09

In their 80s, they embarked on a 7 day fast

10:14

specifically because they wanted to ignite what happens during

10:17

autophagy. Now they'd been in ketosis for several months and they've done a 12-hour fast, a 24-hour fast and even a

10:25

36-hour fast. They did them without much trouble and were able to have a pretty positive

10:31

experience when fasting. After reading and learning about autophagy they wanted to do a 7 day fast.

10:38

I wouldn't recommend this to most patients in their 80s,

10:40

but they had quick access to me and they were great about checking their biomarkers. They checked their blood pressure

10:46

They checked their blood sugar and they checked their blood ketones and they had quick access to me

10:51

With that process they made it to day four, five, six and all the way through the seventh day without any calories.

10:59

I can guarantee that inside their eighty year old body

11:02

they awoke cells that had been dormant for many years cleaning up the crew trying any little morsel of a debris

11:10

that's not being used.

11:11

They ignited their cleanup crew to do things their body shouldn't have done at 80 years old in today's world

11:19

But going back a couple hundred years

11:21

this wasn't that uncommon. To have times when food was scarce for seven days is not an unheard-of

11:28

situation. Today's access to food has made autophagy almost a thing of the past.

11:33

And I would contend that until this Nobel Prize came out

11:37

Most of my colleagues didn't even know about the word either. I want to close by saying autophagy is

11:43

the scientific word that says eat thyself

11:46

It is ignited when your body has been in ketosis and you go with no calories for 12 hours or more

11:53

You can induce autophagy from a carbohydrate loaded diet

11:57

But it takes many more days and it's very difficult

12:00

using this newfound science gives us a great tool to guide patients in ways to help clean up the debris from their

12:08

chronically inflamed brains, bodies, and tummies. I hope this was helpful

12:13

It was kind of sciency but it's a really cool understanding of what happens inside our bodies

12:17

I'd love to hear if you have any comments below so send them to me and I'll try to answer them if you'd like to

12:23

learn more about this ketogenic diet and things like autophagy, you can check out the book I wrote--
12:28
Anyway, You Can that's on audible or on Amazon. Until next time I'm signing off. Dr. Boz

No comments:

Post a Comment